From Edinburgh take the M8 towards Glasgow, at junction 17 take the A82 exit to Dumbarton. Then as you enter Glasgow take the Great Western Road (A82 signs for Kelvinside), which leads to Botanic Gardens.
From Buchanan Bus Station take the number 6 bus, from Glasgow Central take bus no.s 7 or 6, from Sauchiehall Street in Glasgow take bus number 4A. From Glasgow airport take the number 500 bus. The nearest subway station to Botanic Gardens is Hillhead station on the Glasgow Subway. The nearest central railway station is Partick or Hyndland.